Version 5.4
Homo sapiens Gene: RANBP9
Summary
InnateDB Gene IDBG-62534.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RANBP9
Gene Name RAN binding protein 9
Synonyms BPM-L; BPM90; RanBP7; RANBPM
Species Homo sapiens
Ensembl Gene ENSG00000010017
Encoded Proteins
IDBP-62536
RAN binding protein 9
IDBP-603885
RAN binding protein 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 18040864
RANBP9 is located in the Microtubule-Organizing Center it contains protein-interaction motifs, a cytoskeletal-binding domain, and multiple canonical docking sites for signalling intermediates. RANBP9 acts as an scaffolding protein and is important for maintaining cellular functions in the immune and nervous system.
Entrez Gene
Summary This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:13621498-13711564
Strand Reverse strand
Band p23
Transcripts
ENST00000011619 ENSP00000011619
ENST00000469916
ENST00000539980 ENSP00000438162
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 136 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 136 [view]
Protein-Protein 136 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008536 Ran GTPase binding
GO:0019899 enzyme binding
Biological Process
GO:0006461 protein complex assembly
GO:0007020 microtubule nucleation
GO:0007411 axon guidance
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005875 microtubule associated complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038546
View Gene Order
ENSBTAG00000021556
Not yet available
Pathways
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
met_pathway
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
ar_pathway
Coregulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.708182 Hs.732354
RefSeq NM_005493 XM_006714945
HUGO
OMIM
CCDS CCDS4529
HPRD 04835
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca