Version 5.4
Homo sapiens Gene: TIPARP
Summary
InnateDB Gene IDBG-62730.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TIPARP
Gene Name TCDD-inducible poly(ADP-ribose) polymerase
Synonyms ARTD14; PARP7; pART14
Species Homo sapiens
Ensembl Gene ENSG00000163659
Encoded Proteins
IDBP-62732
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-475893
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-480751
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-479611
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-474853
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-479176
TCDD-inducible poly(ADP-ribose) polymerase
IDBP-591805
TCDD-inducible poly(ADP-ribose) polymerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:156673235-156706770
Strand Forward strand
Band q25.31
Transcripts
ENST00000295924 ENSP00000295924
ENST00000486483 ENSP00000418757
ENST00000461166 ENSP00000420612
ENST00000473702 ENSP00000419982
ENST00000481853 ENSP00000418829
ENST00000495891 ENSP00000420141
ENST00000542783 ENSP00000438345
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0035326 enhancer binding
GO:0046872 metal ion binding
Biological Process
GO:0001570 vasculogenesis
GO:0001822 kidney development
GO:0006471 protein ADP-ribosylation
GO:0006807 nitrogen compound metabolic process
GO:0008209 androgen metabolic process
GO:0008210 estrogen metabolic process
GO:0008585 female gonad development
GO:0009791 post-embryonic development
GO:0010629 negative regulation of gene expression
GO:0030097 hemopoiesis
GO:0044236 multicellular organismal metabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0048745 smooth muscle tissue development
GO:0060021 palate development
GO:0060325 face morphogenesis
GO:0071407 cellular response to organic cyclic compound
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034640
View Gene Order
ENSBTAG00000012120
Not yet available
Cross-References
SwissProt
TrEMBL C9JXM5 G5E9W1
UniProt Splice Variant
Entrez Gene 25976
UniGene Hs.12813 Hs.630820
RefSeq NM_001184717 NM_001184718 NM_015508
HUGO HGNC:23696
OMIM 612480
CCDS CCDS3177
HPRD 18192
IMGT
EMBL AC092927 AC106708 CH471052
GenPept EAW78726 EAW78727
RNA Seq Atlas 25976

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca