InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RHOU

Summary

InnateDB Gene

IDBG-628393.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RHOU

Gene Name

Rho-related GTP-binding protein RhoU

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018691

Encoded Proteins

IDBP-679747

Rho-related GTP-binding protein RhoU

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116574:
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 28:2167764-2177307

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000024876

ENSBTAP00000024876

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0046872	metal ion binding

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0007010	cytoskeleton organization
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0008360	regulation of cell shape
GO:0015031	protein transport
GO:0016601	Rac protein signal transduction
GO:0030036	actin cytoskeleton organization

Cellular Component

GO:0000139	Golgi membrane
GO:0002102	podosome
GO:0005622	intracellular
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0030054	cell junction
GO:0042995	cell projection