Bos taurus Gene: VPS37A | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-628693.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | VPS37A | ||||||||||
Gene Name | vacuolar protein sorting-associated protein 37A | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000010355 | ||||||||||
Encoded Proteins |
vacuolar protein sorting-associated protein 37A
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155975:
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 27:19018677-19052353 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Membrane binding and targetting of GAG proteins pathway
Late Phase of HIV Life Cycle pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
Synthesis And Processing Of GAG, GAGPOL Polyproteins pathway
HIV Life Cycle pathway
HIV Infection pathway
Assembly Of The HIV Virion pathway
Budding and maturation of HIV virion pathway
Disease pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
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KEGG |
Endocytosis pathway
Endocytosis pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Bt.27829 Bt.73891 | ||||||||||
RefSeq | NM_001046161 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||