|Bos taurus Gene: BRD2|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||Bromodomain-containing protein 2|
Bromodomain-containing protein 2
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204256:
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
|Genomic Location||Chromosome 23:7240060-7247225|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
Regulation of retinoblastoma protein
|UniProt Splice Variant|
|RefSeq||NM_001045866 XM_005223209 XM_005223210 XM_005223211 XM_005223212 XM_005223213|
|RNA Seq Atlas||505358|