Bos taurus Protein: BRD2 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-680266.2 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | BRD2 | ||||||||||
Protein Name | Bromodomain-containing protein 2 | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Protein | ENSBTAP00000014704 | ||||||||||
InnateDB Gene | IDBG-628888 (BRD2) | ||||||||||
Protein Structure |
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UniProt Annotation | |||||||||||
Function | Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly (By similarity). May play a role in spermatogenesis or folliculogenesis (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Nucleus {ECO:0000250}. Note=Detected on chromatin and nucleosomes. {ECO:0000250}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR001487
Bromodomain |
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PFAM |
PF00439
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PRINTS |
PR00503
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PIRSF | |||||||||||
SMART |
SM00297
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q32S26 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 505358 | ||||||||||
UniGene | Bt.33281 | ||||||||||
RefSeq | NP_001039331 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AY957499 | ||||||||||
GenPept | AAY34703 | ||||||||||