Version 5.4
Bos taurus Gene: BT.53810
Summary
InnateDB Gene IDBG-628997.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.53810
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019309
Encoded Proteins
IDBP-680399
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187240:
This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:5633896-5693059
Strand Reverse strand
Band
Transcripts
ENSBTAT00000025708 ENSBTAP00000025708
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0042384 cilium assembly
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000187240
View Gene Order
ENSMUSG00000047193
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_228134
Signaling by Hedgehog pathway
REACT_111102
Signal Transduction pathway
REACT_267634
Hedgehog 'off' state pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_269412
Hedgehog 'off' state pathway
REACT_230745
Immune System pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_229531
Adaptive Immune System pathway
REACT_250064
Signaling by Hedgehog pathway
REACT_188257
Signal Transduction pathway
KEGG
hsa04962
Vasopressin-regulated water reabsorption pathway
hsa04145
Phagosome pathway
mmu04962
Vasopressin-regulated water reabsorption pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BAY6
UniProt Splice Variant
Entrez Gene 512287
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02039860 DAAA02039861 DAAA02039862
GenPept
RNA Seq Atlas 512287

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca