Version 5.4
Homo sapiens Gene: REM1
Summary
InnateDB Gene IDBG-62900.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REM1
Gene Name RAS (RAD and GEM)-like GTP-binding 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000088320
Encoded Proteins
IDBP-62902
RAS (RAD and GEM)-like GTP-binding 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:31475293-31484905
Strand Forward strand
Band q11.21
Transcripts
ENST00000201979 ENSP00000201979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005516 calmodulin binding
GO:0005525 GTP binding
GO:0015093 ferrous iron transmembrane transporter activity
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0015684 ferrous iron transport
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000359
View Gene Order
ENSBTAG00000014176
Not yet available
Cross-References
SwissProt O75628
TrEMBL
UniProt Splice Variant
Entrez Gene 28954
UniGene Hs.247729
RefSeq NM_014012
HUGO HGNC:15922
OMIM 610388
CCDS CCDS13181
HPRD
IMGT
EMBL AF084465 AF152863 AK313060 AL121751 BC039813 BT020078 BT020079 CH471077
GenPept AAC33132 AAF74212 AAH39813 AAV38881 AAV38882 BAG35890 CAB90274 EAW76439 EAW76440 EAW76442
RNA Seq Atlas 28954

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca