InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: INPP4B

Summary

InnateDB Gene

IDBG-629544.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INPP4B

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014111

Encoded Proteins

IDBP-680979

inositol polyphosphate-4-phosphatase, type II, 105kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109452:
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:15722310-16066444

Strand

Forward strand

Band

Transcripts

ENSBTAT00000018761

ENSBTAP00000018761

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008289	lipid binding
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity

Biological Process

GO:0006874	cellular calcium ion homeostasis
GO:0016311	dephosphorylation
GO:0045671	negative regulation of osteoclast differentiation
GO:0046822	regulation of nucleocytoplasmic transport
GO:0046850	regulation of bone remodeling
GO:0051896	regulation of protein kinase B signaling