Homo sapiens Gene: INPP4B | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-39125.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | INPP4B | ||||||||||||||||||||||
Gene Name | inositol polyphosphate-4-phosphatase, type II, 105kDa | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000109452 | ||||||||||||||||||||||
Encoded Proteins |
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
inositol polyphosphate-4-phosphatase, type II, 105kDa
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 4:142023160-142847432 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | q31.21 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Synthesis of PIPs at the plasma membrane pathway
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of IP2, IP, and Ins in the cytosol pathway
Metabolism of lipids and lipoproteins pathway
PI Metabolism pathway
Phospholipid metabolism pathway
Inositol phosphate metabolism pathway
Metabolism pathway
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KEGG |
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
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INOH |
Inositol phosphate metabolism pathway
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PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | E9PHC0 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 8821 | ||||||||||||||||||||||
UniGene | Hs.531403 Hs.604960 Hs.732573 | ||||||||||||||||||||||
RefSeq | NM_001101669 NM_003866 XM_005263323 XM_005263325 XM_006714401 XM_006714402 | ||||||||||||||||||||||
HUGO | HGNC:6075 | ||||||||||||||||||||||
OMIM | 607494 | ||||||||||||||||||||||
CCDS | CCDS3757 | ||||||||||||||||||||||
HPRD | 06322 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AC093860 AC093885 AC108060 AC108077 AC138657 AC139720 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 8821 | ||||||||||||||||||||||