InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.88405

Summary

InnateDB Gene

IDBG-629705.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.88405

Gene Name

F-box only protein 4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000016981

Encoded Proteins

IDBP-681120

F-box only protein 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151876:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 20:32606049-32618895

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000022583

ENSBTAP00000022583

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0000209	protein polyubiquitination
GO:0000723	telomere maintenance
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0016567	protein ubiquitination
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031398	positive regulation of protein ubiquitination