Bos taurus Gene: RGS5
Summary
InnateDB Gene IDBG-629788.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS5
Gene Name Regulator of G-protein signaling 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016341
Encoded Proteins
Regulator of G-protein signaling 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143248:
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:6228349-6426528
Strand Forward strand
Band
Transcripts
ENSBTAT00000032193 ENSBTAP00000032130
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0009968 negative regulation of signal transduction
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
GPCR signaling pathway
GPCR signaling pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q3T0T8
TrEMBL
UniProt Splice Variant
Entrez Gene 540509
UniGene Bt.92767
RefSeq NM_001034707
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102265
GenPept AAI02266
RNA Seq Atlas 540509
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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