Version 5.4
Bos taurus Gene: CCRN4L
Summary
InnateDB Gene IDBG-629822.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCRN4L
Gene Name nocturnin
Synonyms NOC
Species Bos taurus
Ensembl Gene ENSBTAG00000005998
Encoded Proteins
IDBP-681237
nocturnin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151014:
The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:18892763-18910926
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007876 ENSBTAP00000007876
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005515 protein binding
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0007623 circadian rhythm
GO:0009991 response to extracellular stimulus
GO:0010629 negative regulation of gene expression
GO:0032496 response to lipopolysaccharide
GO:0032922 circadian regulation of gene expression
GO:0033962 cytoplasmic mRNA processing body assembly
GO:0042752 regulation of circadian rhythm
GO:0045600 positive regulation of fat cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045995 regulation of embryonic development
GO:0048255 mRNA stabilization
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000151014
View Gene Order
ENSMUSG00000023087
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111118
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
REACT_24941
Circadian Clock pathway
REACT_241925
Circadian Clock pathway
REACT_198620
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2VE74 A6QPV9
UniProt Splice Variant
Entrez Gene 540641
UniGene Bt.27843
RefSeq NM_001082454
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133608 BC149515 DAAA02044446
GenPept AAI33609 AAI49516
RNA Seq Atlas 540641

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca