Mus musculus Gene: Ccrn4l
Summary
InnateDB Gene IDBG-142661.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccrn4l
Gene Name CCR4 carbon catabolite repression 4-like (S. cerevisiae)
Synonyms AU043840; Ccr4; nocturnin;
Species Mus musculus
Ensembl Gene ENSMUSG00000023087
Encoded Proteins
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151014:
The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:51224447-51251644
Strand Forward strand
Band C
Transcripts
ENSMUST00000023849 ENSMUSP00000023849
ENSMUST00000144826
ENSMUST00000167780 ENSMUSP00000130347
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0006397 mRNA processing
GO:0007623 circadian rhythm
GO:0009991 response to extracellular stimulus
GO:0010629 negative regulation of gene expression
GO:0032496 response to lipopolysaccharide
GO:0032922 circadian regulation of gene expression
GO:0033962 cytoplasmic mRNA processing body assembly
GO:0042752 regulation of circadian rhythm
GO:0045600 positive regulation of fat cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045995 regulation of embryonic development
GO:0048255 mRNA stabilization
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Circadian Clock pathway
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Circadian Clock pathway
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.422145 Mm.474178 Mm.86541
RefSeq NM_009834 XM_006500956
OMIM
CCDS CCDS17336
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas