Version 5.4
Bos taurus Gene: HOOK3
Summary
InnateDB Gene IDBG-629989.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOOK3
Gene Name protein Hook homolog 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007634
Encoded Proteins
IDBP-681443
hook homolog 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168172:
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:37278344-37358417
Strand Forward strand
Band
Transcripts
ENSBTAT00000010044 ENSBTAP00000010044
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0042802 identical protein binding
Biological Process
GO:0007032 endosome organization
GO:0007040 lysosome organization
GO:0008333 endosome to lysosome transport
GO:0016192 vesicle-mediated transport
GO:0022027 interkinetic nuclear migration
GO:0031122 cytoplasmic microtubule organization
GO:0034454 microtubule anchoring at centrosome
GO:0045022 early endosome to late endosome transport
GO:0050768 negative regulation of neurogenesis
GO:0051645 Golgi localization
GO:0071539 protein localization to centrosome
GO:0097150 neuronal stem cell maintenance
Cellular Component
GO:0000242 pericentriolar material
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0016020 membrane
GO:0030897 HOPS complex
GO:0034451 centriolar satellite
GO:0070695 FHF complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000168172
View Gene Order
ENSMUSG00000037234
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.72537
RefSeq NM_001192600 XM_005226117
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca