InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BRIP1

Summary

InnateDB Gene

IDBG-630001.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BRIP1

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012068

Encoded Proteins

IDBP-681451

BRCA1 interacting protein C-terminal helicase 1

IDBP-681459

BRCA1 interacting protein C-terminal helicase 1

IDBP-681460

BRCA1 interacting protein C-terminal helicase 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136492:
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:11495503-11669266

Strand

Forward strand

Band

Transcripts

ENSBTAT00000061499	ENSBTAP00000053187
ENSBTAT00000048969	ENSBTAP00000045921
ENSBTAT00000065712	ENSBTAP00000055345

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004003	ATP-dependent DNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity
GO:0016817	hydrolase activity, acting on acid anhydrides
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Biological Process

GO:0006139	nucleobase-containing compound metabolic process
GO:0006200	ATP catabolic process
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0032508	DNA duplex unwinding