Version 5.4
Bos taurus Gene: REXO2
Summary
InnateDB Gene IDBG-630697.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REXO2
Gene Name Oligoribonuclease, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005843
Encoded Proteins
IDBP-682175
Oligoribonuclease, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000076043:
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
This gene encodes a 3\'-to-5\' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:25293299-25304051
Strand Forward strand
Band
Transcripts
ENSBTAT00000007680 ENSBTAP00000007680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0008152 metabolic process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0005925 focal adhesion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000076043
View Gene Order
ENSMUSG00000032026
View Gene Order
Cross-References
SwissProt A2VE52
TrEMBL V6F7X8
UniProt Splice Variant
Entrez Gene 540139
UniGene Bt.57665
RefSeq NM_001081735
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133575 GJ062397
GenPept AAI33576 DAA22392
RNA Seq Atlas 540139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca