Bos taurus Gene: PRPH2
InnateDB Gene IDBG-631103.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPH2
Gene Name Peripherin-2
Synonyms RDS
Species Bos taurus
Ensembl Gene ENSBTAG00000005971
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112619:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:16376206-16390351
Strand Reverse strand
ENSBTAT00000007836 ENSBTAP00000007836
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007155 cell adhesion
GO:0007601 visual perception
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Homo sapiens
Mus musculus
Gene ID
Gene Order
SwissProt P17810
UniProt Splice Variant
Entrez Gene 280907
UniGene Bt.12752
RefSeq NM_001166487
EMBL DAAA02055075 J02884
GenPept AAA30693
RNA Seq Atlas 280907