Mus musculus Gene: Prph2
InnateDB Gene IDBG-188526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prph2
Gene Name peripherin 2
Synonyms AOFMD; AVMD; Nmf193; PRPH; Rd-2; Rd2; Rds; RP7; Tspan22
Species Mus musculus
Ensembl Gene ENSMUSG00000023978
Encoded Proteins
peripherin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112619:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46910459-46924933
Strand Forward strand
Band C
ENSMUST00000024773 ENSMUSP00000024773
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007155 cell adhesion
GO:0007601 visual perception
GO:0009645 response to low light intensity stimulus
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0016021 integral component of membrane
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt P15499
UniProt Splice Variant
Entrez Gene 19133
RefSeq NM_008938
MGI ID MGI:102791
MGI Symbol Prph2
EMBL AK136280 BC028958 BC085266 CH466559 L42167 X14770
GenPept AAC37674 AAH28958 AAH85266 BAE22911 CAA32878 EDL23547
RNA Seq Atlas 19133