Bos taurus Gene: KLHDC3
Summary
InnateDB Gene IDBG-631419.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHDC3
Gene Name Kelch domain-containing protein 3
Synonyms C23H6orf153
Species Bos taurus
Ensembl Gene ENSBTAG00000012746
Encoded Proteins
Kelch domain-containing protein 3
Kelch domain-containing protein 3
Kelch domain-containing protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124702:
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:16627392-16638402
Strand Forward strand
Band
Transcripts
ENSBTAT00000016943 ENSBTAP00000016943
ENSBTAT00000016944 ENSBTAP00000016944
ENSBTAT00000047039 ENSBTAP00000044278
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0007126 meiotic nuclear division
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
IRE1alpha activates chaperones pathway
Metabolism of proteins pathway
XBP1(S) activates chaperone genes pathway
Unfolded Protein Response (UPR) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
XBP1(S) activates chaperone genes pathway
IRE1alpha activates chaperones pathway
Unfolded Protein Response (UPR) pathway
Metabolism of proteins pathway
Unfolded Protein Response (UPR) pathway
Metabolism of proteins pathway
IRE1alpha activates chaperones pathway
XBP1(S) activates chaperone genes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A6QNR1 Q58CV6
TrEMBL Q58D25
UniProt Splice Variant
Entrez Gene 541138
UniGene Bt.101030 Bt.4489
RefSeq NM_001014966 NM_001105479
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103002 BC148959 BT020656 BT021772 BT021774 BT021841 DAAA02055080
GenPept AAI03003 AAI48960 AAX08673 AAX46619 AAX46621 AAX46688
RNA Seq Atlas 100125879 541138