Bos taurus Gene: KRT5
Summary
InnateDB Gene IDBG-631845.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT5
Gene Name keratin, type II cytoskeletal 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000038384
Encoded Proteins
keratin, type II cytoskeletal 5
keratin, type II cytoskeletal 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186081:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:27541327-27547599
Strand Forward strand
Band
Transcripts
ENSBTAT00000021456 ENSBTAP00000021456
ENSBTAT00000009478 ENSBTAP00000009478
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0097110 scaffold protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045095 keratin filament
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
Type I hemidesmosome assembly pathway
Cell-Cell communication pathway
Cell junction organization pathway
Type I hemidesmosome assembly pathway
Cell junction organization pathway
Cell-Cell communication pathway
KEGG
INOH
PID NCI
Glucocorticoid receptor regulatory network
Validated transcriptional targets of deltaNp63 isoforms
Cross-References
SwissProt
TrEMBL A5D7M6
UniProt Splice Variant
Entrez Gene 281268
UniGene Bt.13162
RefSeq NM_001008663
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140616 DAAA02012886
GenPept AAI40617
RNA Seq Atlas 281268
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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