InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PVRL3

Summary

InnateDB Gene

IDBG-632147.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PVRL3

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013769

Encoded Proteins

IDBP-683751

poliovirus receptor-related 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177707:
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:56353745-56378308

Strand

Forward strand

Band

Transcripts

ENSBTAT00000032332

ENSBTAP00000032266

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0050839	cell adhesion molecule binding

Biological Process

GO:0002089	lens morphogenesis in camera-type eye
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion
GO:0009566	fertilization
GO:0016337	single organismal cell-cell adhesion
GO:0060042	retina morphogenesis in camera-type eye

Cellular Component

GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005913	cell-cell adherens junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043296	apical junction complex