Version 5.4
| Bos taurus Gene: CBLL1 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-632254.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | CBLL1 | ||||||||||||
| Gene Name | E3 ubiquitin-protein ligase Hakai | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000018348 | ||||||||||||
| Encoded Proteins |
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105879:
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 4:49037768-49052388 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME | |||||||||||||
| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI |
Posttranslational regulation of adherens junction stability and dissassembly
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| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | F1MEB7 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 524139 | ||||||||||||
| UniGene | Bt.61292 | ||||||||||||
| RefSeq | NM_001192592 XM_005205418 XM_005205419 XM_005205420 XM_005205421 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | DAAA02010594 | ||||||||||||
| GenPept | |||||||||||||
| RNA Seq Atlas | 524139 | ||||||||||||