InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TAZ

Summary

InnateDB Gene

IDBG-632892.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAZ

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007456

Encoded Proteins

IDBP-684636

tafazzin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102125:
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:40379111-40387392

Strand

Forward strand

Band

Transcripts

ENSBTAT00000009807

ENSBTAP00000009807

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016746	transferase activity, transferring acyl groups
GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity

Biological Process

GO:0006936	muscle contraction
GO:0007507	heart development
GO:0007519	skeletal muscle tissue development
GO:0008152	metabolic process
GO:0030097	hemopoiesis
GO:0032049	cardiolipin biosynthetic process
GO:0032981	mitochondrial respiratory chain complex I assembly
GO:0042407	cristae formation
GO:0042775	mitochondrial ATP synthesis coupled electron transport
GO:0048738	cardiac muscle tissue development
GO:0060048	cardiac muscle contraction