InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: HCLS1

Summary

InnateDB Gene

IDBG-633047.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HCLS1

Gene Name

hematopoietic lineage cell-specific protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000001009

Encoded Proteins

IDBP-684719

hematopoietic lineage cell-specific protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000180353:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:66720537-66754184

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000001338

ENSBTAP00000001338

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001085	RNA polymerase II transcription factor binding
GO:0003779	actin binding
GO:0005515	protein binding
GO:0017124	SH3 domain binding
GO:0019901	protein kinase binding
GO:0032403	protein complex binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0008284	positive regulation of cell proliferation
GO:0009725	response to hormone
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030041	actin filament polymerization
GO:0030218	erythrocyte differentiation
GO:0030833	regulation of actin filament polymerization
GO:0030854	positive regulation of granulocyte differentiation
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
GO:0042993	positive regulation of transcription factor import into nucleus
GO:0045651	positive regulation of macrophage differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0051897	positive regulation of protein kinase B signaling
GO:0071345	cellular response to cytokine stimulus
GO:2000107	negative regulation of leukocyte apoptotic process