Bos taurus Gene: BT.29087 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-633058.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | BT.29087 | ||||||||||||||||
Gene Name | ATP-binding cassette sub-family G member 8 | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000016366 | ||||||||||||||||
Encoded Proteins |
ATP-binding cassette sub-family G member 8
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143921:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 11:26156648-26174650 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
ABCA transporters in lipid homeostasis pathway
ABC-family proteins mediated transport pathway
Trafficking of dietary sterols pathway
Transmembrane transport of small molecules pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
Trafficking of dietary sterols pathway
Metabolism pathway
ABCA transporters in lipid homeostasis pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Transmembrane transport of small molecules pathway
ABC-family proteins mediated transport pathway
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KEGG |
ABC transporters pathway
Fat digestion and absorption pathway
Bile secretion pathway
ABC transporters pathway
Bile secretion pathway
Fat digestion and absorption pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | F1N3K2 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 508829 | ||||||||||||||||
UniGene | Bt.29087 | ||||||||||||||||
RefSeq | NM_001024663 XM_005212594 | ||||||||||||||||
HUGO | HGNC:13887 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | DAAA02030676 DAAA02030677 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 508829 | ||||||||||||||||