Version 5.4
Bos taurus Gene: BT.51496
Summary
InnateDB Gene IDBG-633666.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.51496
Gene Name protein disulfide-isomerase A2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016575
Encoded Proteins
IDBP-685392
protein disulfide-isomerase A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185615:
Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:309841-312520
Strand Forward strand
Band
Transcripts
ENSBTAT00000048134 ENSBTAP00000045224
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0031545 peptidyl-proline 4-dioxygenase activity
Biological Process
GO:0006457 protein folding
GO:0008152 metabolic process
GO:0019511 peptidyl-proline hydroxylation
GO:0034976 response to endoplasmic reticulum stress
GO:0045454 cell redox homeostasis
GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Cellular Component
GO:0005783 endoplasmic reticulum
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000185615
View Gene Order
ENSMUSG00000024184
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
Cross-References
SwissProt
TrEMBL F1N602 M5FJR9
UniProt Splice Variant
Entrez Gene 504356
UniGene Bt.51496
RefSeq NM_001098861
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057275 GJ062847
GenPept DAA15544
RNA Seq Atlas 504356

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca