|Bos taurus Gene: ADAM22|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||disintegrin and metalloproteinase domain-containing protein 22 precursor|
ADAM metallopeptidase domain 22
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000008277:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]
|Genomic Location||Chromosome 4:72691793-72763460|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|EMBL||DAAA02011019 DAAA02011020 DAAA02011021 DAAA02011022|
|RNA Seq Atlas||523645|