Mus musculus Gene: Adam22 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-133249.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Adam22 | ||||||||||||||||||||||
Gene Name | a disintegrin and metallopeptidase domain 22 | ||||||||||||||||||||||
Synonyms | 2900022I03Rik; AI854032; MDC2 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000040537 | ||||||||||||||||||||||
Encoded Proteins |
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
a disintegrin and metallopeptidase domain 22
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000008277:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 5:8072352-8368160 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | A1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.275895 Mm.394078 Mm.447658 Mm.456949 | ||||||||||||||||||||||
RefSeq | NM_001007220 NM_001007221 NM_001098225 XM_006503535 XM_006503537 XM_006503538 XM_006503539 XM_006503540 XM_006503541 XM_006503542 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS19080 CCDS51411 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||