Version 5.4
Bos taurus Gene: ESPN
Summary
InnateDB Gene IDBG-633851.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ESPN
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006515
Encoded Proteins
IDBP-685598
espin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187017:
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:47757077-47791502
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045529 ENSBTAP00000042910
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0007626 locomotory behavior
GO:0030046 parallel actin filament bundle assembly
GO:0051017 actin filament bundle assembly
GO:0051491 positive regulation of filopodium assembly
GO:0051494 negative regulation of cytoskeleton organization
Cellular Component
GO:0015629 actin cytoskeleton
GO:0032421 stereocilium bundle
GO:0032426 stereocilium bundle tip
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000187017
View Gene Order
ENSMUSG00000028943
View Gene Order
Cross-References
SwissProt
TrEMBL E1BHC8
UniProt Splice Variant
Entrez Gene 539821
UniGene
RefSeq
HUGO HGNC:13281
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02043084 DAAA02043085 DAAA02043086 DAAA02043087
GenPept
RNA Seq Atlas 539821

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca