Homo sapiens Gene: TSKS
Summary
InnateDB Gene IDBG-63400.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSKS
Gene Name testis-specific serine kinase substrate
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000126467
Encoded Proteins
testis-specific serine kinase substrate
testis-specific serine kinase substrate
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:49739753-49763330
Strand Reverse strand
Band q13.33
Transcripts
ENST00000358830 ENSP00000351691
ENST00000246801 ENSP00000246801
ENST00000599325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005814 centriole
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9UJT2
TrEMBL C9K0I0
UniProt Splice Variant
Entrez Gene 60385
UniGene Hs.515858
RefSeq NM_021733 XM_005259130
HUGO HGNC:30719
OMIM 608253
CCDS CCDS12780
HPRD
IMGT
EMBL AC011495 AF200923 AF411384 BC058862
GenPept AAF12819 AAH58862 AAL60464
RNA Seq Atlas 60385