|Homo sapiens Gene: MYO3A|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||myosin IIIA|
|Useful resources||Stemformatics EHFPI ImmGen|
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 10:25934267-26212527|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|EMBL||AL162503 AL358612 AL360217 AL391812|
|RNA Seq Atlas||53904|