Bos taurus Gene: ASGR1
Summary
InnateDB Gene IDBG-634567.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASGR1
Gene Name asialoglycoprotein receptor 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012071
Encoded Proteins
asialoglycoprotein receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141505:
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:27529097-27532634
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016010 ENSBTAP00000016010
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0031668 cellular response to extracellular stimulus
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.88328
RefSeq NM_001037590 XM_005220205 XM_005220206
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas