Version 5.4
Bos taurus Gene: EIF5A
Summary
InnateDB Gene IDBG-634772.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF5A
Gene Name Eukaryotic translation initiation factor 5A-1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002018
Encoded Proteins
IDBP-686563
Eukaryotic translation initiation factor 5A-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000253626:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:27648382-27653256
Strand Forward strand
Band
Transcripts
ENSBTAT00000002616 ENSBTAP00000002616
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0006452 translational frameshifting
GO:0006810 transport
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
GO:0015031 protein transport
GO:0043065 positive regulation of apoptotic process
GO:0045901 positive regulation of translational elongation
GO:0045905 positive regulation of translational termination
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000078812
View Gene Order
ENSG00000253626
View Gene Order
Pathways
NETPATH
REACTOME
REACT_205598
Hypusine synthesis from eIF5A-lysine pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_206715
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_229541
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
REACT_203391
Hypusine synthesis from eIF5A-lysine pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6EWQ7
TrEMBL
UniProt Splice Variant
Entrez Gene 444990
UniGene Bt.105866 Bt.65059
RefSeq NM_001003658 XM_005220196
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AJ577608 AJ577609 BC108135
GenPept AAI08136 CAE12193 CAE12194
RNA Seq Atlas 444990

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca