Version 5.4
Bos taurus Gene: NOXO1
Summary
InnateDB Gene IDBG-634901.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOXO1
Gene Name Uncharacterized protein
Synonyms NOXO1
Species Bos taurus
Ensembl Gene ENSBTAG00000020369
Encoded Proteins
IDBP-686707
NADPH oxidase organizer 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196408:
This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:1536097-1538058
Strand Reverse strand
Band
Transcripts
ENSBTAT00000047285 ENSBTAP00000044503
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0019899 enzyme binding
GO:0035091 phosphatidylinositol binding
GO:0042802 identical protein binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0022617 extracellular matrix disassembly
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0043020 NADPH oxidase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000196408
View Gene Order
ENSMUSG00000019320
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
rac1_pathway
RAC1 signaling pathway
Cross-References
SwissProt
TrEMBL E1BAA4
UniProt Splice Variant
Entrez Gene 516233
UniGene
RefSeq XM_002697857 XM_594385
HUGO HGNC:19404
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057306
GenPept
RNA Seq Atlas 516233

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca