Version 5.4
Bos taurus Gene: BT.29990
Summary
InnateDB Gene IDBG-635090.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.29990
Gene Name ectonucleoside triphosphate diphosphohydrolase 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006768
Encoded Proteins
IDBP-686946
ectonucleoside triphosphate diphosphohydrolase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197217:
This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:71419941-71457015
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061167 ENSBTAP00000053633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0045134 uridine-diphosphatase activity
Biological Process
GO:0006256 UDP catabolic process
Cellular Component
GO:0030173 integral component of Golgi membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000197217
View Gene Order
ENSMUSG00000095463
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa04142
Lysosome pathway
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
mmu04142
Lysosome pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1N7A1
UniProt Splice Variant
Entrez Gene 531411
UniGene Bt.102970 Bt.67253
RefSeq XM_005210276 XM_005210277
HUGO HGNC:14573
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02023583 DAAA02023584 DAAA02023585 DAAA02023586
GenPept
RNA Seq Atlas 531411

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca