Bos taurus Gene: BT.86861
Summary
InnateDB Gene IDBG-635609.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.86861
Gene Name actin-related protein 2
Synonyms ARP2
Species Bos taurus
Ensembl Gene ENSBTAG00000009761
Encoded Proteins
actin-related protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138071:
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:63552997-63591980
Strand Forward strand
Band
Transcripts
ENSBTAT00000012872 ENSBTAP00000012872
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007163 establishment or maintenance of cell polarity
GO:0008356 asymmetric cell division
GO:0016344 meiotic chromosome movement towards spindle pole
GO:0016482 cytoplasmic transport
GO:0030036 actin cytoskeleton organization
GO:0033206 cytokinesis after meiosis
GO:0051321 meiotic cell cycle
GO:0051653 spindle localization
Cellular Component
GO:0005938 cell cortex
GO:0016020 membrane
GO:0030478 actin cap
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
KitReceptor pathway
REACTOME
Regulation of actin dynamics for phagocytic cup formation pathway
Developmental Biology pathway
EPHB-mediated forward signaling pathway
Innate Immune System pathway
Axon guidance pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
EPH-Ephrin signaling pathway
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Immune System pathway
EPH-Ephrin signaling pathway
EPHB-mediated forward signaling pathway
Axon guidance pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
ErbB1 downstream signaling
RAC1 signaling pathway
CDC42 signaling events
PDGFR-beta signaling pathway
Cross-References
SwissProt
TrEMBL F1MRG7
UniProt Splice Variant
Entrez Gene 538486
UniGene Bt.111559 Bt.3684
RefSeq NM_001102213
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031453 DAAA02031454 DAAA02031455 DAAA02031456 DAAA02031457 DAAA02031458 DAAA02031459
GenPept
RNA Seq Atlas 538486