Bos taurus Gene: GPSM2
Summary
InnateDB Gene IDBG-635667.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPSM2
Gene Name G-protein-signaling modulator 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017124
Encoded Proteins
G-protein signaling modulator 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121957:
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:34545729-34580297
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022762 ENSBTAP00000022762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030695 GTPase regulator activity
GO:0042802 identical protein binding
Biological Process
GO:0000132 establishment of mitotic spindle orientation
GO:0050790 regulation of catalytic activity
GO:0060487 lung epithelial cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0045177 apical part of cell
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL E1BIX7
UniProt Splice Variant
Entrez Gene 513654
UniGene Bt.2150
RefSeq NM_001192355
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007580
GenPept
RNA Seq Atlas 513654