Version 5.4
Homo sapiens Gene: DDX55
Summary
InnateDB Gene IDBG-63579.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDX55
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111364
Encoded Proteins
IDBP-63581
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
IDBP-63583
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
IDBP-594954
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
IDBP-599085
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
IDBP-593543
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
IDBP-600000
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been confirmed. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:123602077-123620941
Strand Forward strand
Band q24.31
Transcripts
ENST00000238146 ENSP00000238146
ENST00000354291 ENSP00000346244
ENST00000421670 ENSP00000442332
ENST00000542286
ENST00000544429
ENST00000545042
ENST00000544738 ENSP00000442823
ENST00000540763 ENSP00000446255
ENST00000538744 ENSP00000443114
ENST00000536079
ENST00000539934
ENST00000541259
ENST00000543016
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016787 hydrolase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
Cellular Component
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029389
View Gene Order
ENSBTAG00000007266
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.599964
RefSeq NM_020936 XM_005253591
HUGO
OMIM
CCDS CCDS9251
HPRD 13130
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca