Version 5.4
Bos taurus Gene: EIF3M
Summary
InnateDB Gene IDBG-636267.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF3M
Gene Name eukaryotic translation initiation factor 3 subunit M
Synonyms HFL-B5
Species Bos taurus
Ensembl Gene ENSBTAG00000005338
Encoded Proteins
IDBP-688186
eukaryotic translation initiation factor 3 subunit M
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149100:
This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:64095495-64112928
Strand Forward strand
Band
Transcripts
ENSBTAT00000007021 ENSBTAP00000007021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0002183 cytoplasmic translational initiation
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000149100
View Gene Order
ENSMUSG00000027170
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N5F7
UniProt Splice Variant
Entrez Gene 515543
UniGene
RefSeq NM_001035312
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02041245
GenPept
RNA Seq Atlas 515543

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca