InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PLA2G3

Summary

InnateDB Gene

IDBG-636673.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLA2G3

Gene Name

Group 3 secretory phospholipase A2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011962

Encoded Proteins

IDBP-688624

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100078:
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:72087169-72092223

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000015876

ENSBTAP00000015876

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004623	phospholipase A2 activity
GO:0005509	calcium ion binding

Biological Process

GO:0001675	acrosome assembly
GO:0006644	phospholipid metabolic process
GO:0007288	sperm axoneme assembly
GO:0016042	lipid catabolic process
GO:0019372	lipoxygenase pathway
GO:0043303	mast cell degranulation
GO:0046470	phosphatidylcholine metabolic process
GO:0048468	cell development
GO:0060271	cilium morphogenesis