|Bos taurus Gene: PDCD10|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||programmed cell death protein 10|
programmed cell death 10
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114209:
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 1:100540220-100587970|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
Validated targets of C-MYC transcriptional activation
|UniProt Splice Variant|
|RefSeq||NM_001075259 XM_005201716 XM_005201717|
|RNA Seq Atlas|