InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.64477

Summary

InnateDB Gene

IDBG-636890.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.64477

Gene Name

glutathione S-transferase kappa 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009839

Encoded Proteins

IDBP-688863

glutathione S-transferase kappa 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197448:
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:107468164-107473271

Strand

Forward strand

Band

Transcripts

ENSBTAT00000012969

ENSBTAP00000012969

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 91 interaction(s) predicted by orthology.

Predicted by orthology
Total	91 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0004602	glutathione peroxidase activity
GO:0005102	receptor binding
GO:0015035	protein disulfide oxidoreductase activity

Biological Process

GO:0006749	glutathione metabolic process
GO:0030855	epithelial cell differentiation
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005622	intracellular
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005777	peroxisome
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome