InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: GDF7

Summary

InnateDB Gene

IDBG-637592.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GDF7

Gene Name

growth/differentiation factor 7 precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000038224

Encoded Proteins

IDBP-689616

Growth differentiation factor-7Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143869:
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:78270223-78274248

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000056229

ENSBTAP00000052102

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0007411	axon guidance
GO:0010628	positive regulation of gene expression
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0021509	roof plate formation
GO:0021527	spinal cord association neuron differentiation
GO:0021915	neural tube development
GO:0022612	gland morphogenesis
GO:0030509	BMP signaling pathway
GO:0030855	epithelial cell differentiation
GO:0030901	midbrain development
GO:0032924	activin receptor signaling pathway
GO:0040007	growth
GO:0045165	cell fate commitment
GO:0045666	positive regulation of neuron differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048608	reproductive structure development
GO:0048754	branching morphogenesis of an epithelial tube
GO:0048853	forebrain morphogenesis
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0060571	morphogenesis of an epithelial fold
GO:2001051	positive regulation of tendon cell differentiation