InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ALDH3A2

Summary

InnateDB Gene

IDBG-637716.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ALDH3A2

Gene Name

fatty aldehyde dehydrogenase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000039161

Encoded Proteins

IDBP-689748

fatty aldehyde dehydrogenase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072210:
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:34522835-34538828

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000056266

ENSBTAP00000050170

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003995	acyl-CoA dehydrogenase activity
GO:0004029	aldehyde dehydrogenase (NAD) activity
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
GO:0016491	oxidoreductase activity
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0046577	long-chain-alcohol oxidase activity
GO:0050061	long-chain-aldehyde dehydrogenase activity
GO:0052814	medium-chain-aldehyde dehydrogenase activity

Biological Process

GO:0006081	cellular aldehyde metabolic process
GO:0006714	sesquiterpenoid metabolic process
GO:0007417	central nervous system development
GO:0007422	peripheral nervous system development
GO:0008152	metabolic process
GO:0008218	bioluminescence
GO:0008544	epidermis development
GO:0033306	phytol metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005777	peroxisome
GO:0005783	endoplasmic reticulum
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome