Version 5.4
Bos taurus Gene: PDE6C
Summary
InnateDB Gene IDBG-637732.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDE6C
Gene Name cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000445
Encoded Proteins
IDBP-689763
cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095464:
This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4). [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:14956031-15009228
Strand Forward strand
Band
Transcripts
ENSBTAT00000000569 ENSBTAP00000000569
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0008152 metabolic process
GO:0046549 retinal cone cell development
GO:0050953 sensory perception of light stimulus
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000095464
View Gene Order
ENSMUSG00000024992
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00230
Purine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
cone_pathway
Visual signal transduction: Cones
Cross-References
SwissProt
TrEMBL E1BKB8
UniProt Splice Variant
Entrez Gene 281975
UniGene Bt.444
RefSeq NM_174419 XM_005225438 XM_005225442 XM_005225443
HUGO HGNC:8787
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058833
GenPept
RNA Seq Atlas 281975

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca