Version 5.4
Mus musculus Gene: Pde6c
Summary
InnateDB Gene IDBG-162765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pde6c
Gene Name phosphodiesterase 6C, cGMP specific, cone, alpha prime
Synonyms cpfl1
Species Mus musculus
Ensembl Gene ENSMUSG00000024992
Encoded Proteins
IDBP-162767
phosphodiesterase 6C, cGMP specific, cone, alpha prime
IDBP-256236
phosphodiesterase 6C, cGMP specific, cone, alpha prime
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095464:
This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4). [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:38132781-38183947
Strand Forward strand
Band C2
Transcripts
ENSMUST00000025956 ENSMUSP00000025956
ENSMUST00000112329 ENSMUSP00000107948
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 protein binding
GO:0030553 cGMP binding
GO:0046872 metal ion binding
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
Biological Process
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0008152 metabolic process
GO:0046549 retinal cone cell development
GO:0050953 sensory perception of light stimulus
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000095464
View Gene Order
ENSBTAG00000000445
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
cone_pathway
Visual signal transduction: Cones
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.450141
RefSeq NM_001170959 NM_033614
OMIM
CCDS CCDS37971 CCDS50431
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca