InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MCM5

Summary

InnateDB Gene

IDBG-637921.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MCM5

Gene Name

DNA replication licensing factor MCM5

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015595

Encoded Proteins

IDBP-689970

DNA replication licensing factor MCM5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100297:
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:73990687-74009154

Strand

Forward strand

Band

Transcripts

ENSBTAT00000020715

ENSBTAP00000020715

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.

Predicted by orthology
Total	44 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003678	DNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016787	hydrolase activity