Version 5.4
Bos taurus Gene: UGCG
Summary
InnateDB Gene IDBG-638018.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UGCG
Gene Name ceramide glucosyltransferase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016073
Encoded Proteins
IDBP-690059
ceramide glucosyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148154:
Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:102987421-103024296
Strand Forward strand
Band
Transcripts
ENSBTAT00000043826 ENSBTAP00000041368
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0008152 metabolic process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000148154
View Gene Order
ENSMUSG00000028381
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116105
Glycosphingolipid metabolism pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_199008
Glycosphingolipid metabolism pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
il2_pi3kpathway
IL2 signaling events mediated by PI3K
Cross-References
SwissProt
TrEMBL Q08DR4
UniProt Splice Variant
Entrez Gene 514357
UniGene Bt.56578
RefSeq NM_001076850
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123602 DAAA02024529 DAAA02024530 DAAA02024531
GenPept AAI23603
RNA Seq Atlas 514357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca