Mus musculus Gene: Ugcg
Summary
InnateDB Gene IDBG-151201.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ugcg
Gene Name UDP-glucose ceramide glucosyltransferase
Synonyms AU043821; C80537; Epcs21; GlcT-1; Ugcgl;
Species Mus musculus
Ensembl Gene ENSMUSG00000028381
Encoded Proteins
UDP-glucose ceramide glucosyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148154:
Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:59189257-59222833
Strand Forward strand
Band B3
Transcripts
ENSMUST00000030074 ENSMUSP00000030074
ENSMUST00000133996
ENSMUST00000128227
ENSMUST00000155153
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008120 ceramide glucosyltransferase activity
Biological Process
GO:0006665 sphingolipid metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
KEGG
Sphingolipid metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycosphingolipid metabolism pathway
Metabolism pathway
KEGG
Sphingolipid metabolism pathway
INOH
PID BIOCARTA
PID NCI
IL2 signaling events mediated by PI3K
Cross-References
SwissProt O88693
TrEMBL
UniProt Splice Variant
Entrez Gene 22234
UniGene Mm.198803 Mm.394516
RefSeq NM_011673
OMIM
CCDS CCDS18219
HPRD
IMGT
MGI ID MGI:1332243
MGI Symbol Ugcg
EMBL AB012807 AL808112 BC050828 CH466565 D89866
GenPept AAH50828 BAA28782 BAA33558 CAM26180 EDL02214
RNA Seq Atlas 22234